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Should we routinely measure free plasma phenytoin concentration?

The plasma protein binding of phenytoin was investigated in 56 epileptic patients attending the outpatient clinic. The free phenytoin fraction was measured by equilibrium dialysis at 37 degrees C and the total concentration by a homogenous enzyme immunoassay technique. The free fraction ranged from...

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Detalles Bibliográficos
Main Authors: Rimmer, E M, Buss, D C, Routledge, P A, Richens, A
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463310/
https://ncbi.nlm.nih.gov/pubmed/6419764
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