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Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin
Pax6 and c-Maf regulate multiple stages of mammalian lens development. Here, we identified novel distal control regions (DCRs) of the αA-crystallin gene, a marker of lens fiber cell differentiation induced by FGF-signaling. DCR1 stimulated reporter gene expression in primary lens explants treated wi...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462985/ https://ncbi.nlm.nih.gov/pubmed/16675956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601114 |
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