Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin

Pax6 and c-Maf regulate multiple stages of mammalian lens development. Here, we identified novel distal control regions (DCRs) of the αA-crystallin gene, a marker of lens fiber cell differentiation induced by FGF-signaling. DCR1 stimulated reporter gene expression in primary lens explants treated wi...

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Main Authors: Yang, Ying, Stopka, Tomáš, Golestaneh, Nady, Wang, Yan, Wu, Kongming, Li, Anping, Chauhan, Bharesh K, Gao, Chun Y, Cveklová, Květa, Duncan, Melinda K, Pestell, Richard G, Chepelinsky, Ana B, Skoultchi, Arthur I, Cvekl, Aleš
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462985/
https://ncbi.nlm.nih.gov/pubmed/16675956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601114
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