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The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing
The underlying mechanisms linking antisense RNA, chromatin architecture and gene expression have not been fully elucidated. Here we show that long transcripts encoded from the Kcnq1ot1 antisense promoter silence the flanking genes more efficiently than short antisense transcripts. Interestingly, the...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462980/ https://ncbi.nlm.nih.gov/pubmed/16628224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601090 |
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