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The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution rates: implications for the correlation between the synonymous substitution rate and codon usage bias.

Most methods for estimating the rate of synonymous and nonsynonymous substitution per site define a site as a mutational opportunity: the proportion of sites that are synonymous is equal to the proportion of mutations that would be synonymous under the model of evolution being considered. Here we de...

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Bibliografski detalji
Glavni autori: Bierne, Nicolas, Eyre-Walker, Adam
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462865/
https://ncbi.nlm.nih.gov/pubmed/14668405
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