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Genetic and phenotypic analysis of alleles of the Drosophila chromosomal JIL-1 kinase reveals a functional requirement at multiple developmental stages.

In this study we provide a cytological and genetic characterization of the JIL-1 locus in Drosophila. JIL-1 is an essential chromosomal tandem kinase and in JIL-1 null animals chromatin structure is severely perturbed. Using a range of JIL-1 hypomorphic mutations, we show that they form an allelic s...

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Bibliografiske detaljer
Main Authors: Zhang, Weiguo, Jin, Ye, Ji, Yun, Girton, Jack, Johansen, Jørgen, Johansen, Kristen M
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462823/
https://ncbi.nlm.nih.gov/pubmed/14668387
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