Increasing the distance between the snRNA promoter and the 3' box decreases the efficiency of snRNA 3'-end formation.

Chimeric genes which contained the mouse U1b snRNA promoter, portions of the histone H2a or globin coding regions and the U1b 3'-end followed by a histone 3'-end were constructed. The distance between the U1 promoter and the U1 3' box was varied between 146 and 670 nt. The chimeric ge...

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Hauptverfasser: Ramamurthy, L, Ingledue, T C, Pilch, D R, Kay, B K, Marzluff, W F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC146281/
https://ncbi.nlm.nih.gov/pubmed/8948645
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