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Increasing the distance between the snRNA promoter and the 3' box decreases the efficiency of snRNA 3'-end formation.

Chimeric genes which contained the mouse U1b snRNA promoter, portions of the histone H2a or globin coding regions and the U1b 3'-end followed by a histone 3'-end were constructed. The distance between the U1 promoter and the U1 3' box was varied between 146 and 670 nt. The chimeric genes were introd...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Ramamurthy, L, Ingledue, T C, Pilch, D R, Kay, B K, Marzluff, W F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4525
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