Undulated short-tail deletion mutation in the mouse ablates Pax1 and leads to ectopic activation of neighboring Nkx2-2 in domains that normally express Pax1.

Previous studies have indicated that the Undulated short-tail deletion mutation in mouse Pax1 (Pax1(Un-s)) not only ablates Pax1, but also disturbs a gene or genes nearby Pax1. However, which gene(s) is involved and how the Pax1(Un-s) phenotype is confined to the Pax1-positive tissues remain unknown...

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Detalhes bibliográficos
Main Authors: Kokubu, Chikara, Wilm, Bettina, Kokubu, Tomoko, Wahl, Matthias, Rodrigo, Isabel, Sakai, Norio, Santagati, Fabio, Hayashizaki, Yoshihide, Suzuki, Misao, Yamamura, Ken-Ichi, Abe, Kuniya, Imai, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462742/
https://ncbi.nlm.nih.gov/pubmed/14504237
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