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A method for detecting recent selection in the human genome from allele age estimates.

Mutations that have recently increased in frequency by positive natural selection are an important component of naturally occurring variation that affects fitness. To identify such variants, we developed a method to test for recent selection by estimating the age of an allele from the extent of hapl...

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Detalhes bibliográficos
Main Authors: Toomajian, Christopher, Ajioka, Richard S, Jorde, Lynn B, Kushner, James P, Kreitman, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462736/
https://ncbi.nlm.nih.gov/pubmed/14504236
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