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Maximum-Likelihood Methods for Detecting Recent Positive Selection and Localizing the Selected Site in the Genome

Two maximum-likelihood methods are proposed for detecting recent, strongly positive selection and for localizing the target of selection along a recombining chromosome. The methods utilize the compact mutation frequency spectrum at multiple neutral loci that are partially linked to the selected site...

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Bibliografiske detaljer
Main Authors: Li, Haipeng, Stephan, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2005 by the Genetics Society of America 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456529/
https://ncbi.nlm.nih.gov/pubmed/15972464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.041368
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