Targeted nucleotide repair of cyc1 mutations in Saccharomyces cerevisiae directed by modified single-stranded DNA oligonucleotides.

Modified single-stranded DNA oligonucleotides have been used to direct base changes in the CYC1 gene of Saccharomyces cerevisiae. In this process, the oligonucleotide is believed to hybridize to the target site through the action of a DNA recombinase and, once bound, DNA repair enzymes act to excise...

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Hlavní autoři: Brachman, Erin E, Kmiec, Eric B
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462467/
https://ncbi.nlm.nih.gov/pubmed/12618392
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