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Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae.

SIR2 proteins have NAD(+)-dependent histone deacetylase activity, but no metabolic role has been assigned to any of these proteins. In Salmonella enterica, SIR2 function was required for activity of the acetyl-CoA synthetase (Acs) enzyme. A greater than two orders of magnitude increase in the specif...

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Bibliografski detalji
Glavni autori: Starai, Vincent J, Takahashi, Hidekazu, Boeke, Jef D, Escalante-Semerena, Jorge C
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462443/
https://ncbi.nlm.nih.gov/pubmed/12618394
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