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Estimation of effective population size of HIV-1 within a host: a pseudomaximum-likelihood approach.

Using pseudomaximum-likelihood approaches to phylogenetic inference and coalescent theory, we develop a computationally tractable method of estimating effective population size from serially sampled viral data. We show that the variance of the maximum-likelihood estimator of effective population siz...

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Autori principali: Seo, Tae-Kun, Thorne, Jeffrey L, Hasegawa, Masami, Kishino, Hirohisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462041/
https://ncbi.nlm.nih.gov/pubmed/11973287
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