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Estimates of natural selection due to protein tertiary structure inform the ancestry of biallelic loci
We consider the inference of which of two alleles is ancestral when the alleles have a single nonsynonymous difference and when natural selection acts via protein tertiary structure. Whereas the probability that an allele is ancestral under neutrality is equal to its frequency, under selection this...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715921/ https://ncbi.nlm.nih.gov/pubmed/18725272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.07.020 |
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