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Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans.

The Toll-like receptor 4 protein acts as the transducing subunit of the lipopolysaccharide receptor complex and assists in the detection of Gram-negative pathogens within the mammalian host. Several lines of evidence support the view that variation at the TLR4 locus may alter host susceptibility to...

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Autors principals: Smirnova, I, Hamblin, M T, McBride, C, Beutler, B, Di Rienzo, A
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461767/
https://ncbi.nlm.nih.gov/pubmed/11514453
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