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The amino-terminal domain of the transcription termination factor TTF-I causes protein oligomerization and inhibition of DNA binding.

The transcription termination factor TTF-I binds specifically to an 18 bp DNA element in the murine ribosomal gene spacer and mediates termination of RNA polymerase I transcription. In this study, we have compared DNA binding and termination activity of recombinant full-length TTF-I (TTF-Ip130) with...

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Udgivet i:Nucleic Acids Res
Principais autores: Sander, E E, Mason, S W, Munz, C, Grummt, I
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8871544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.19.3677
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