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The amino-terminal domain of the transcription termination factor TTF-I causes protein oligomerization and inhibition of DNA binding.

The transcription termination factor TTF-I binds specifically to an 18 bp DNA element in the murine ribosomal gene spacer and mediates termination of RNA polymerase I transcription. In this study, we have compared DNA binding and termination activity of recombinant full-length TTF-I (TTF-Ip130) with...

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Autori principali: Sander, E E, Mason, S W, Munz, C, Grummt, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC146174/
https://ncbi.nlm.nih.gov/pubmed/8871544
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