Goalpha regulates volatile anesthetic action in Caenorhabditis elegans.

To identify genes controlling volatile anesthetic (VA) action, we have screened through existing Caenorhabditis elegans mutants and found that strains with a reduction in Go signaling are VA resistant. Loss-of-function mutants of the gene goa-1, which codes for the alpha-subunit of Go, have EC(50)s...

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Bibliografiske detaljer
Main Authors: van Swinderen, B, Metz, L B, Shebester, L D, Mendel, J E, Sternberg, P W, Crowder, C M
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461665/
https://ncbi.nlm.nih.gov/pubmed/11404329
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