The G-protein beta-subunit GPB-2 in Caenorhabditis elegans regulates the G(o)alpha-G(q)alpha signaling network through interactions with the regulator of G-protein signaling proteins EGL-10 and EAT-16.

The genome of Caenorhabditis elegans harbors two genes for G-protein beta-subunits. Here, we describe the characterization of the second G-protein beta-subunit gene gpb-2. In contrast to gpb-1, gpb-2 is not an essential gene even though, like gpb-1, gpb-2 is expressed during development, in the nerv...

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Bibliographic Details
Main Authors: van der Linden, A M, Simmer, F, Cuppen, E, Plasterk, R H
Format: Artigo
Language:Inglês
Published: 2001
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461628/
https://ncbi.nlm.nih.gov/pubmed/11333232
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