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The implications of intergenic polymorphism for major histocompatibility complex evolution.

A systematic survey of six intergenic regions flanking the human HLA-B locus in eight haplotypes reveals the regions to be up to 20 times more polymorphic than the reported average degree of human neutral polymorphism. Furthermore, the extent of polymorphism is directly related to the proximity to t...

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Autori principali: O'hUigin, C, Satta, Y, Hausmann, A, Dawkins, R L, Klein, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461294/
https://ncbi.nlm.nih.gov/pubmed/11014832
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