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The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.

p53 is a transcription factor that binds double-stranded (ds) DNA in a sequence-specific manner. In addition, p53 can bind the ends of single-stranded (ss) DNA. We previously demonstrated that ssDNA oligonucleotides interact with the C-terminal domain of p53 and stimulate binding to internal segment...

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Detalhes bibliográficos
Main Authors: Selivanova, G, Iotsova, V, Kiseleva, E, Ström, M, Bakalkin, G, Grafström, R C, Wiman, K G
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146129/
https://ncbi.nlm.nih.gov/pubmed/8836183
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