The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.
p53 is a transcription factor that binds double-stranded (ds) DNA in a sequence-specific manner. In addition, p53 can bind the ends of single-stranded (ss) DNA. We previously demonstrated that ssDNA oligonucleotides interact with the C-terminal domain of p53 and stimulate binding to internal segment...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8836183/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.18.3560 |
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