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The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.

p53 is a transcription factor that binds double-stranded (ds) DNA in a sequence-specific manner. In addition, p53 can bind the ends of single-stranded (ss) DNA. We previously demonstrated that ssDNA oligonucleotides interact with the C-terminal domain of p53 and stimulate binding to internal segment...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Selivanova, G, Iotsova, V, Kiseleva, E, Ström, M, Bakalkin, G, Grafström, R C, Wiman, K G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146129/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8836183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.18.3560
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