The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains.

The mutagen-sensitive-101 (mus101) gene of Drosophila melanogaster was first identified 25 years ago through mutations conferring larval hypersensitivity to DNA-damaging agents. Other alleles of mus101 causing different phenotypes were later isolated: a female sterile allele results in a defect in a...

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Autors principals: Yamamoto, R R, Axton, J M, Yamamoto, Y, Saunders, R D, Glover, D M, Henderson, D S
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461266/
https://ncbi.nlm.nih.gov/pubmed/11014818
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