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Towards artificial ribonucleases: the sequence-specific cleavage of RNA in a duplex.

Lanthanide complexes covalently attached to oligonucleotides have been shown to cleave RNA in a sequence-specific manner. Efficient cleavage, however, is at present limited to single-stranded RNA regions, as RNA in a duplex is considerably more resistant to strand scission. To overcome this limitati...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Hall, J, Hüsken, D, Häner, R
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146125/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8836177/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.18.3522
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