In the TTF-1 homeodomain the contribution of several amino acids to DNA recognition depends on the bound sequence.
The thyroid transcription factor-1 homeodomain (TTF-1HD) shows a peculiar DNA binding specificity, preferentially recognizing sequences containing the 5'-CAAG-3' core motif. Most other homeodomains instead recognize sites containing the 5'-TAAT-3' core motif. Here, we show that TTF-1HD efficiently r...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8811078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.17.3283 |
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