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In the TTF-1 homeodomain the contribution of several amino acids to DNA recognition depends on the bound sequence.

The thyroid transcription factor-1 homeodomain (TTF-1HD) shows a peculiar DNA binding specificity, preferentially recognizing sequences containing the 5'-CAAG-3' core motif. Most other homeodomains instead recognize sites containing the 5'-TAAT-3' core motif. Here, we show that T...

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Hlavní autoři: Fabbro, D, Tell, G, Leonardi, A, Pellizzari, L, Pucillo, C, Lonigro, R, Formisano, S, Damante, G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC146104/
https://ncbi.nlm.nih.gov/pubmed/8811078
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