In the TTF-1 homeodomain the contribution of several amino acids to DNA recognition depends on the bound sequence.

The thyroid transcription factor-1 homeodomain (TTF-1HD) shows a peculiar DNA binding specificity, preferentially recognizing sequences containing the 5'-CAAG-3' core motif. Most other homeodomains instead recognize sites containing the 5'-TAAT-3' core motif. Here, we show that TTF-1HD efficiently r...

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में प्रकाशित:	Nucleic Acids Res
मुख्य लेखकों:	Fabbro, D, Tell, G, Leonardi, A, Pellizzari, L, Pucillo, C, Lonigro, R, Formisano, S, Damante, G
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Oxford University Press 1996
विषय:	Research Article
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8811078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.17.3283
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