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Identification of in vivo target RNA sequences bound by thymidylate synthase.

We developed an immunoprecipitation-RNA-random PCR (rPCR) method to isolate cellular RNA sequences that bind to the folate-dependent enzyme thymidylate synthase (TS). Using this approach, nine different cellular RNAs that formed a ribonucleoprotein (RNP) complex with thymidylate synthase (TS) in hum...

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Detalles Bibliográficos
Main Authors: Chu, E, Cogliati, T, Copur, S M, Borre, A, Voeller, D M, Allegra, C J, Segal, S
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC146086/
https://ncbi.nlm.nih.gov/pubmed/8774904
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