Intron homing with limited exon homology. Illegitimate double-strand-break repair in intron acquisition by phage t4.

The td intron of bacteriophage T4 encodes a DNA endonuclease that initiates intron homing to cognate intronless alleles by a double-strand-break (DSB) repair process. A genetic assay was developed to analyze the relationship between exon homology and homing efficiency. Because models predict exonucl...

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Bibliographische Detailangaben
Hauptverfasser: Parker, M M, Belisle, M, Belfort, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460845/
https://ncbi.nlm.nih.gov/pubmed/10581262
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