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The DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxes.

The formation of a near complete loop of DNA is a striking property of the architectural HMG-box factor xUBF. Here we show that DNA looping only requires a dimer of Nbox13, a C-terminal truncation mutant of xUBF containing just HMG-boxes 1-3. This segment of xUBF corresponds to that minimally requir...

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Detalhes bibliográficos
Main Authors: Stefanovsky, V Y, Bazett-Jones, D P, Pelletier, G, Moss, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146074/
https://ncbi.nlm.nih.gov/pubmed/8774902
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