The DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxes.

The formation of a near complete loop of DNA is a striking property of the architectural HMG-box factor xUBF. Here we show that DNA looping only requires a dimer of Nbox13, a C-terminal truncation mutant of xUBF containing just HMG-boxes 1-3. This segment of xUBF corresponds to that minimally requir...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Stefanovsky, V Y, Bazett-Jones, D P, Pelletier, G, Moss, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8774902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.16.3208
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