In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin.

Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide which binds with high affinity to the largest subunit of RNAPII, RPB1. We have found that in murine fibroblasts exposure to alpha-amanitin triggered degradation of the RPB...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Nucleic Acids Res
Autori principali:	Nguyen, V T, Giannoni, F, Dubois, M F, Seo, S J, Vigneron, M, Kédinger, C, Bensaude, O
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.2924
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!