In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin.

Alpha-Amanitin is a well-known specific inhibitor of RNA polymerase II (RNAPII) in vitro and in vivo. It is a cyclic octapeptide which binds with high affinity to the largest subunit of RNAPII, RPB1. We have found that in murine fibroblasts exposure to alpha-amanitin triggered degradation of the RPB...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Nguyen, V T, Giannoni, F, Dubois, M F, Seo, S J, Vigneron, M, Kédinger, C, Bensaude, O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.2924
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!