The Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 genes are required for tolerating irreparable, ultraviolet-induced DNA damage.

In wild-type Saccharomyces cerevisiae, a checkpoint slows the rate of progression of an ongoing S phase in response to exposure to a DNA-alkylating agent. Mutations that eliminate S phase regulation also confer sensitivity to alkylating agents, leading us to suggest that, by regulating the S phase r...

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Bibliographic Details
Main Authors: Paulovich, A G, Armour, C D, Hartwell, L H
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460327/
https://ncbi.nlm.nih.gov/pubmed/9725831
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