Catalytic mechanism of quinoprotein methanol dehydrogenase: A theoretical and x-ray crystallographic investigation

The catalytic mechanism of the reductive half reaction of the quinoprotein methanol dehydrogenase (MDH) is believed to proceed either through a hemiketal intermediate or by direct transfer of a hydride ion from the substrate methyl group to the cofactor, pyrroloquinoline quinone (PQQ). A crystal str...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Zheng, Ya-Jun, Xia, Zong-xiang, Chen, Zhi-wei, Mathews, F. Scott, Bruice, Thomas C.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2001
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11149955/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021547498
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