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Catalytic mechanism of quinoprotein methanol dehydrogenase: A theoretical and x-ray crystallographic investigation

The catalytic mechanism of the reductive half reaction of the quinoprotein methanol dehydrogenase (MDH) is believed to proceed either through a hemiketal intermediate or by direct transfer of a hydride ion from the substrate methyl group to the cofactor, pyrroloquinoline quinone (PQQ). A crystal str...

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Main Authors: Zheng, Ya-Jun, Xia, Zong-xiang, Chen, Zhi-wei, Mathews, F. Scott, Bruice, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC14603/
https://ncbi.nlm.nih.gov/pubmed/11149955
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