Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes.
RNA substrates which form relatively short helices I and III with hammerhead ribozymes are generally cleaved more rapidly than substrates which create longer binding helices. We speculated that for optimum cleavage rates, one of the helices needed to be relatively weak. To identify this helix, a ser...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8758995/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.14.2679 |
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