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Solid-phase synthesis of oligo-2-pyrimidinone-2'-deoxyribonucleotides and oligo-2-pyrimidinone-2'-deoxyriboside methylphosphonates.

A synthetic method was developed for the synthesis of oligodeoxyribonucleotides and oligodeoxyribonucleoside methylphosphonates comprised exclusively of the fluorescent 2-pyrimidinone base for the first time. The method utilized the solid-phase 2-cyanoethylphosphoramidite and methylphosphonamidite c...

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Pubblicato in:Nucleic Acids Res
Autori principali: Zhou, Y, Ts'o, P O
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1996
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8758991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.14.2652
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