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Chlorpyrifos Affects Phenotypic Outcomes in a Model of Mammalian Neurodevelopment: Critical Stages Targeting Differentiation in PC12 Cells

The organophosphate insecticide chlorpyrifos (CPF) adversely affects mammalian brain development through multiple mechanisms. To determine if CPF directly affects neuronal cell replication and phenotypic fate, and to identify the vulnerable stages of differentiation, we exposed PC12 cells, a model f...

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Main Authors: Jameson, Ruth R., Seidler, Frederic J., Qiao, Dan, Slotkin, Theodore A.
Format: Artigo
Jezik:Inglês
Izdano: National Institute of Environmental Health Sciences 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459917/
https://ncbi.nlm.nih.gov/pubmed/16675418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.8750
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