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Differential antitumor immunity mediated by NKT cell subsets in vivo

We showed previously that NKT cell–deficient TCR Jα18(−/−) mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor surveillance can be restored by adoptive transfer of WT liver-derived NKT cells. Liver-derived NKT cells were used in these studies because of thei...

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Bibliographische Detailangaben
Hauptverfasser: Crowe, Nadine Y., Coquet, Jonathan M., Berzins, Stuart P., Kyparissoudis, Konstantinos, Keating, Rachael, Pellicci, Daniel G., Hayakawa, Yoshihiro, Godfrey, Dale I., Smyth, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459911/
https://ncbi.nlm.nih.gov/pubmed/16275765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050953
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