IL-21 Modulates Activation of NKT Cells in Patients with Stage IV Malignant Melanoma

Interleukin-21 (IL-21) is a common γ-chain cytokine produced by T helper and natural killer T (NKT) cells. It has been shown to regulate the response of various lymphocyte subsets including NK, NKT, T and B cells. Owing to its potent anti-tumor function in preclinical studies and its ability to indu...

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Bibliografiske detaljer
Udgivet i:Clin Transl Immunology
Main Authors: Coquet, Jonathan M, Skak, Kresten, Davis, Ian D, Smyth, Mark J, Godfrey, Dale I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232058/
https://ncbi.nlm.nih.gov/pubmed/25505948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2013.7
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