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A C-Terminal Domain Targets the Pseudomonas aeruginosa Cytotoxin ExoU to the Plasma Membrane of Host Cells

ExoU, a phospholipase injected into host cells by the type III secretion system of Pseudomonas aeruginosa, leads to rapid cytolytic cell death. Although the importance of ExoU in infection is well established, the mechanism by which this toxin kills host cells is less clear. To gain insight into how...

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Detalhes bibliográficos
Main Authors: Rabin, Shira D. P., Veesenmeyer, Jeffrey L., Bieging, Kathryn T., Hauser, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459758/
https://ncbi.nlm.nih.gov/pubmed/16622190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2552-2561.2006
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