A C-Terminal Domain Targets the Pseudomonas aeruginosa Cytotoxin ExoU to the Plasma Membrane of Host Cells

ExoU, a phospholipase injected into host cells by the type III secretion system of Pseudomonas aeruginosa, leads to rapid cytolytic cell death. Although the importance of ExoU in infection is well established, the mechanism by which this toxin kills host cells is less clear. To gain insight into how...

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Bibliographische Detailangaben
Hauptverfasser: Rabin, Shira D. P., Veesenmeyer, Jeffrey L., Bieging, Kathryn T., Hauser, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459758/
https://ncbi.nlm.nih.gov/pubmed/16622190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2552-2561.2006
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