Expression of Haemophilus ducreyi Collagen Binding Outer Membrane Protein NcaA Is Required for Virulence in Swine and Human Challenge Models of Chancroid

Haemophilus ducreyi, the etiologic agent of the sexually transmitted genital ulcer disease chancroid, has been shown to associate with dermal collagen fibers within infected skin lesions. Here we describe NcaA, a previously uncharacterized outer membrane protein that is important for H. ducreyi coll...

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Bibliographic Details
Main Authors: Fulcher, Robert A., Cole, Leah E., Janowicz, Diane M., Toffer, Kristen L., Fortney, Kate R., Katz, Barry P., Orndorff, Paul E., Spinola, Stanley M., Kawula, Thomas H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459755/
https://ncbi.nlm.nih.gov/pubmed/16622201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2651-2658.2006
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