Expression of Haemophilus ducreyi Collagen Binding Outer Membrane Protein NcaA Is Required for Virulence in Swine and Human Challenge Models of Chancroid

Haemophilus ducreyi, the etiologic agent of the sexually transmitted genital ulcer disease chancroid, has been shown to associate with dermal collagen fibers within infected skin lesions. Here we describe NcaA, a previously uncharacterized outer membrane protein that is important for H. ducreyi coll...

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Detalhes bibliográficos
Main Authors: Fulcher, Robert A., Cole, Leah E., Janowicz, Diane M., Toffer, Kristen L., Fortney, Kate R., Katz, Barry P., Orndorff, Paul E., Spinola, Stanley M., Kawula, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459755/
https://ncbi.nlm.nih.gov/pubmed/16622201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2651-2658.2006
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