The Mycobacterial 38-Kilodalton Glycolipoprotein Antigen Activates the Mitogen-Activated Protein Kinase Pathway and Release of Proinflammatory Cytokines through Toll-Like Receptors 2 and 4 in Human Monocytes

Although the 38-kDa glycolipoprotein of Mycobacterium tuberculosis H37Rv is known to evoke prominent cellular and humoral immune responses in human tuberculosis (TB), little information is known about intracellular regulatory mechanisms involved in 38-kDa antigen (Ag)-induced host responses. In this...

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Detalhes bibliográficos
Main Authors: Jung, Saet-Byel, Yang, Chul-Su, Lee, Ji-Sook, Shin, A-Rum, Jung, Sung-Soo, Son, Ji Woong, Harding, Clifford V., Kim, Hwa-Jung, Park, Jeong-Kyu, Paik, Tae-Hyun, Song, Chang-Hwa, Jo, Eun-Kyeong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459749/
https://ncbi.nlm.nih.gov/pubmed/16622205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2686-2696.2006
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