The Mycobacterial 38-Kilodalton Glycolipoprotein Antigen Activates the Mitogen-Activated Protein Kinase Pathway and Release of Proinflammatory Cytokines through Toll-Like Receptors 2 and 4 in Human Monocytes

Although the 38-kDa glycolipoprotein of Mycobacterium tuberculosis H37Rv is known to evoke prominent cellular and humoral immune responses in human tuberculosis (TB), little information is known about intracellular regulatory mechanisms involved in 38-kDa antigen (Ag)-induced host responses. In this...

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Main Authors: Jung, Saet-Byel, Yang, Chul-Su, Lee, Ji-Sook, Shin, A-Rum, Jung, Sung-Soo, Son, Ji Woong, Harding, Clifford V., Kim, Hwa-Jung, Park, Jeong-Kyu, Paik, Tae-Hyun, Song, Chang-Hwa, Jo, Eun-Kyeong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459749/
https://ncbi.nlm.nih.gov/pubmed/16622205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2686-2696.2006
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