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Brucella abortus Rough Mutants Induce Macrophage Oncosis That Requires Bacterial Protein Synthesis and Direct Interaction with the Macrophage

Previous studies suggest that smooth Brucella organisms inhibit macrophage apoptosis. In contrast, necrotic cell death of macrophages infected with rough Brucella organisms in vitro has been reported, which may in part explain the failure of some rough organisms to thrive. To characterize these pote...

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Détails bibliographiques
Auteurs principaux: Pei, Jianwu, Turse, Joshua E., Wu, Qingmin, Ficht, Thomas A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459739/
https://ncbi.nlm.nih.gov/pubmed/16622203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2667-2675.2006
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