Partial Reconstitution of the CD4(+)-T-Cell Compartment in CD4 Gene Knockout Mice Restores Responses to Tuberculosis DNA Vaccines

Reactivation tuberculosis (TB) is a serious problem in immunocompromised individuals, especially those with human immunodeficiency virus (HIV) coinfection. The adaptive immune response mediated by CD4(+) and CD8(+) T cells is known to confer protection against TB. Hence, vaccines against TB are desi...

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Detalhes bibliográficos
Main Authors: D'Souza, Sushila, Romano, Marta, Korf, Johanna, Wang, Xiao-Ming, Adnet, Pierre-Yves, Huygen, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459720/
https://ncbi.nlm.nih.gov/pubmed/16622212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2751-2759.2006
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