Leishmania donovani Requires Functional Cdc42 and Rac1 To Prevent Phagosomal Maturation

Leishmania donovani promastigotes survive inside macrophage phagosomes by inhibiting phagosomal maturation. The main surface glycoconjugate on promastigotes, lipophosphoglycan (LPG), is crucial for survival and mediates the formation of a protective shell of F-actin around the phagosome. Previous st...

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Bibliographic Details
Main Authors: Lerm, M., Holm, Å., Seiron, Å., Särndahl, E., Magnusson, K.-E., Rasmusson, B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459716/
https://ncbi.nlm.nih.gov/pubmed/16622197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2613-2618.2006
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