Signal Transduction Mechanism Involved in Clostridium perfringens Alpha-Toxin-Induced Superoxide Anion Generation in Rabbit Neutrophils

Clostridium perfringens alpha-toxin induces the generation of superoxide anion (O(2)(−)) via production of 1,2-diacylglycerol (DG) in rabbit neutrophils. The mechanism of the generation, however, remains poorly understood. Here we report a novel mechanism for the toxin-induced production of O(2)(−)...

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Autors principals: Oda, Masataka, Ikari, Syusuke, Matsuno, Takayuki, Morimune, Yuka, Nagahama, Masahiro, Sakurai, Jun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459708/
https://ncbi.nlm.nih.gov/pubmed/16622226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2876-2886.2006
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